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Different Modes of Transport for (3)H-Thymidine, (3)H-FLT, and (3)H-FMAU in Proliferating and Nonproliferating Human Tumor Cells
The basis for the use of nucleoside tracers in PET is that activity of the cell-growth–dependent enzyme thymidine kinase 1 is the rate-limiting factor driving tracer retention in tumors. Recent publications suggest that nucleoside transporters might influence uptake and thereby affect the tracer sig...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368522/ https://ncbi.nlm.nih.gov/pubmed/20720049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.110.076794 |
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