Global Patterns of Tissue-Specific Alternative Polyadenylation in Drosophila

We analyzed the usage and consequences of alternative cleavage and polyadenylation (APA) in Drosophila melanogaster by using >1 billion reads of stranded mRNA-seq across a variety of dissected tissues. Beyond demonstrating that a majority of fly transcripts are subject to APA, we observed broad t...

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Hauptverfasser: Smibert, Peter, Miura, Pedro, Westholm, Jakub O., Shenker, Sol, May, Gemma, Duff, Michael O., Zhang, Dayu, Eads, Brian D., Carlson, Joe, Brown, James B., Eisman, Robert C., Andrews, Justen, Kaufman, Thomas, Cherbas, Peter, Celniker, Susan E., Graveley, Brenton R., Lai, Eric C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368434/
https://ncbi.nlm.nih.gov/pubmed/22685694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.01.001
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