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Alternative polyadenylation in the nervous system: to what lengths will 3′ UTR extensions take us?

Alternative cleavage and polyadenylation (APA) can diversify coding and non-coding regions, but has particular impact on increasing 3′ UTR diversity. Through the gain or loss of regulatory elements such as RNA binding protein and microRNA sites, APA can influence transcript stability, localization,...

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Vydáno v:Bioessays
Hlavní autoři: Miura, Pedro, Sanfilippo, Piero, Shenker, Sol, Lai, Eric C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503322/
https://ncbi.nlm.nih.gov/pubmed/24903459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300174
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