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Alternative polyadenylation in the nervous system: to what lengths will 3′ UTR extensions take us?

Alternative cleavage and polyadenylation (APA) can diversify coding and non-coding regions, but has particular impact on increasing 3′ UTR diversity. Through the gain or loss of regulatory elements such as RNA binding protein and microRNA sites, APA can influence transcript stability, localization,...

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Detalhes bibliográficos
Publicado no:Bioessays
Main Authors: Miura, Pedro, Sanfilippo, Piero, Shenker, Sol, Lai, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503322/
https://ncbi.nlm.nih.gov/pubmed/24903459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300174
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