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Photocleavage of DNA and photofootprinting of E. coli RNA polymerase bound to promoter DNA by azido-9-acridinylamines.

The long-wavelength ultraviolet (lambda approximately 420 nm) radiation induced reaction between 6-azido-2-methoxy-9-acridinylamines and supercoiled plasmid DNA results in single strand scissions and formation of covalent adducts (ratio approximately 1:10). By treating azidoacridine-photomodified DN...

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Bibliografiske detaljer
Main Authors: Jeppesen, C, Buchardt, O, Henriksen, U, Nielsen, P E
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC336827/
https://ncbi.nlm.nih.gov/pubmed/3041368
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