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DNA conformational analysis in solution by uranyl mediated photocleavage.
Uranyl mediated photocleavage of double stranded DNA is proposed as a general probing for DNA helix conformation in terms of minor groove width/electronegative potential. Specifically, it is found that A/T-tracts known to constitute strong distamycin binding sites are preferentially photocleaved by...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1990
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC331085/ https://ncbi.nlm.nih.gov/pubmed/2374711 |
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