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DNA conformational analysis in solution by uranyl mediated photocleavage.

Uranyl mediated photocleavage of double stranded DNA is proposed as a general probing for DNA helix conformation in terms of minor groove width/electronegative potential. Specifically, it is found that A/T-tracts known to constitute strong distamycin binding sites are preferentially photocleaved by...

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Autors principals: Nielsen, P E, Møllegaard, N E, Jeppesen, C
Format: Artigo
Idioma:Inglês
Publicat: 1990
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC331085/
https://ncbi.nlm.nih.gov/pubmed/2374711
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