Number and Brightness Analysis of LRRK2 Oligomerization in Live Cells

Leucine-rich repeat kinase 2 (LRRK2) is a large multidomain protein that contains enzymatically functional GTPase and kinase domains. Several noncoding LRRK2 gene polymorphisms have been associated with susceptibility to Parkinson's disease (PD), Crohn's disease, and leprosy. Many LRRK2 co...

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Bibliografiske detaljer
Main Authors: James, Nicholas G., Digman, Michelle A., Gratton, Enrico, Barylko, Barbara, Ding, Xiaodong, Albanesi, Joseph P., Goldberg, Matthew S., Jameson, David M.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2012
Fag:
Biophysical Letter
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368136/
https://ncbi.nlm.nih.gov/pubmed/22713584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.046
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