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Involvement of molecular chaperones and the transcription factor Nrf2 in neuroprotection mediated by para-substituted-4,5-diaryl-3-thiomethyl-1,2,4-triazines

Much evidence supports that oxidative stress plays an important role in the pathogenesis of neurodegenerative diseases, such as Alzheimer’s disease. Herein, we studied the compensatory/adaptive mechanisms involved in 3-thiomethyl-5,6-(diphenyl)-1,2,4-triazine and 3-thiomethyl-5,6-(dichlorophenyl)-1,...

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Detalhes bibliográficos
Main Authors: Khodagholi, Fariba, Ansari, Niloufar, Amini, Mohsen, Tusi, Solaleh Khoramian
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368030/
https://ncbi.nlm.nih.gov/pubmed/22212523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-011-0316-0
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