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Visualization of Genomic Changes by Segmented Smoothing Using an L (0) Penalty
Copy number variations (CNV) and allelic imbalance in tumor tissue can show strong segmentation. Their graphical presentation can be enhanced by appropriate smoothing. Existing signal and scatterplot smoothers do not respect segmentation well. We present novel algorithms that use a penalty on the [I...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367998/ https://ncbi.nlm.nih.gov/pubmed/22679492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038230 |
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