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IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis
After their development in the thymus, mature T cells are maintained in the periphery by two sets of survival signals, namely TCR signals from contact with self-peptide/MHC ligands and the cytokine receptor signals from binding IL-7 and IL-15. These signals cooperate to maximize the utility of finit...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367861/ https://ncbi.nlm.nih.gov/pubmed/22551764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2012.04.010 |
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