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IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis

After their development in the thymus, mature T cells are maintained in the periphery by two sets of survival signals, namely TCR signals from contact with self-peptide/MHC ligands and the cytokine receptor signals from binding IL-7 and IL-15. These signals cooperate to maximize the utility of finit...

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Detalhes bibliográficos
Main Authors: Carrette, Florent, Surh, Charles D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367861/
https://ncbi.nlm.nih.gov/pubmed/22551764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2012.04.010
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