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Effects of surface microtopography on the assembly of the osteoclast resorption apparatus
Bone degradation by osteoclasts depends on the formation of a sealing zone, composed of an interlinked network of podosomes, which delimits the degradation lacuna into which osteoclasts secrete acid and proteolytic enzymes. For resorption to occur, the sealing zone must be coherent and stable for ex...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Royal Society
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367804/ https://ncbi.nlm.nih.gov/pubmed/22090285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2011.0659 |
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