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Effects of surface microtopography on the assembly of the osteoclast resorption apparatus

Bone degradation by osteoclasts depends on the formation of a sealing zone, composed of an interlinked network of podosomes, which delimits the degradation lacuna into which osteoclasts secrete acid and proteolytic enzymes. For resorption to occur, the sealing zone must be coherent and stable for ex...

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Autors principals: Geblinger, Dafna, Zink, Christian, Spencer, Nicholas D., Addadi, Lia, Geiger, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367804/
https://ncbi.nlm.nih.gov/pubmed/22090285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2011.0659
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