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Implications of functional similarity for gene regulatory interactions

If one gene regulates another, those two genes are likely to be involved in many of the same biological functions. Conversely, shared biological function may be suggestive of the existence and nature of a regulatory interaction. With this in mind, we develop a measure of functional similarity betwee...

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Bibliografiske detaljer
Main Authors: Glass, Kimberly, Ott, Edward, Losert, Wolfgang, Girvan, Michelle
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367803/
https://ncbi.nlm.nih.gov/pubmed/22298814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2011.0585
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