Disruption of NMDAR–CRMP-2 signaling protects against focal cerebral ischemic damage in the rat middle cerebral artery occlusion model

Collapsin response mediator protein 2 (CRMP-2), traditionally viewed as an axon/dendrite specification and axonal growth protein, has emerged as nidus in regulation of both pre- and post-synaptic Ca(2+) channels. Building on our discovery of the interaction and regulation of Ca(2+) channels by CRMP-...

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Main Authors: Brittain, Joel M., Pan, Rui, You, Haitao, Brustovetsky, Tatiana, Brustovetsky, Nickolay, Zamponi, Gerald W., Lee, Wei-Hua, Khanna, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367672/
https://ncbi.nlm.nih.gov/pubmed/22373559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.18919
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