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Injectable Perlecan Domain 1-Hyaluronan Microgels Potentiate the Cartilage Repair Effect of BMP2 in a Murine Model of Early Osteoarthritis
The goal of this study was to use bioengineered injectable microgels to enhance the action of bone morphogenetic protein 2 (BMP2) and stimulate cartilage matrix repair in a reversible animal model of osteoarthritis (OA). A module of perlecan (PlnD1) bearing heparan sulfate (HS) chains was covalently...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367563/ https://ncbi.nlm.nih.gov/pubmed/22455987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1748-6041/7/2/024109 |
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