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Injectable Perlecan Domain 1-Hyaluronan Microgels Potentiate the Cartilage Repair Effect of BMP2 in a Murine Model of Early Osteoarthritis

The goal of this study was to use bioengineered injectable microgels to enhance the action of bone morphogenetic protein 2 (BMP2) and stimulate cartilage matrix repair in a reversible animal model of osteoarthritis (OA). A module of perlecan (PlnD1) bearing heparan sulfate (HS) chains was covalently...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Srinivasan, Padma P., McCoy, Sarah Y., Jha, Amit K., Yang, Weidong, Jia, Xinqiao, Farach-Carson, Mary C., Kirn-Safran, Catherine B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367563/
https://ncbi.nlm.nih.gov/pubmed/22455987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1748-6041/7/2/024109
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