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Release of the herpes simplex virus 1 protease by self cleavage is required for proper conformation of the portal vertex

We identify an NLS within herpes simplex virus scaffold proteins that is required for optimal nuclear import of these proteins into infected or uninfected nuclei, and is sufficient to mediate nuclear import of GFP. A virus lacking this NLS replicated to titers reduced by 1000-fold, but was able to m...

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Bibliographic Details
Main Authors: Yang, Kui, Wills, Elizabeth G., Baines, Joel D.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367450/
https://ncbi.nlm.nih.gov/pubmed/22543049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.03.009
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