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Release of the herpes simplex virus 1 protease by self cleavage is required for proper conformation of the portal vertex

We identify an NLS within herpes simplex virus scaffold proteins that is required for optimal nuclear import of these proteins into infected or uninfected nuclei, and is sufficient to mediate nuclear import of GFP. A virus lacking this NLS replicated to titers reduced by 1000-fold, but was able to m...

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Detalhes bibliográficos
Main Authors: Yang, Kui, Wills, Elizabeth G., Baines, Joel D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367450/
https://ncbi.nlm.nih.gov/pubmed/22543049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.03.009
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