Anticontractile Effect of Perivascular Adipose Tissue and Leptin are Reduced in Hypertension

Leptin causes vasodilatation both by endothelium-dependent and -independent mechanisms. Leptin is synthesized by perivascular adipose tissue (PVAT). The hypothesis of this study is that a decrease of leptin production in PVAT of spontaneously hypertensive rats (SHR) might contribute to a diminished...

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Detalhes bibliográficos
Main Authors: Gálvez-Prieto, Beatriz, Somoza, Beatriz, Gil-Ortega, Marta, García-Prieto, Concha F., de las Heras, Ana I., González, M. Carmen, Arribas, Silvia, Aranguez, Isabel, Bolbrinker, Juliane, Kreutz, Reinhold, Ruiz-Gayo, Mariano, Fernández-Alfonso, Maria S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367267/
https://ncbi.nlm.nih.gov/pubmed/22679436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00103
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