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Imbalance between Pro and Anti-Oxidant Mechanisms in Perivascular Adipose Tissue Aggravates Long-Term High-Fat Diet-Derived Endothelial Dysfunction

BACKGROUND: The hypothesis of this study is that long-term high-fat diets (HFD) induce perivascular adipose tissue (PVAT) dysfunction characterized by a redox imbalance, which might contribute to aggravate endothelial dysfunction in obesity. METHODS AND RESULTS: C57BL/6J mice were fed either control...

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Detalhes bibliográficos
Main Authors: Gil-Ortega, Marta, Condezo-Hoyos, Luis, García-Prieto, Concha F., Arribas, Silvia M., González, M. Carmen, Aranguez, Isabel, Ruiz-Gayo, Mariano, Somoza, Beatriz, Fernández-Alfonso, María S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997398/
https://ncbi.nlm.nih.gov/pubmed/24760053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095312
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