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Cancer chromosomal instability: therapeutic and diagnostic challenges
Chromosomal instability (CIN)—which is a high rate of loss or gain of whole or parts of chromosomes—is a characteristic of most human cancers and a cause of tumour aneuploidy and intra-tumour heterogeneity. CIN is associated with poor patient outcome and drug resistance, which could be mediated by e...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367245/ https://ncbi.nlm.nih.gov/pubmed/22595889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.61 |
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