Translocator protein (18 kDa) polymorphism (rs6971) explains in-vivo brain binding affinity of the PET radioligand [(18)F]-FEPPA

[(18)F]-FEPPA binds to the 18-kDa translocator protein (TSPO) and is used in positron emission tomography (PET) to detect microglial activation. However, quantitative interpretations of the PET signal with new generation TSPO PET radioligands are confounded by large interindividual variability in bi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mizrahi, Romina, Rusjan, Pablo M, Kennedy, James, Pollock, Bruce, Mulsant, Benoit, Suridjan, Ivonne, De Luca, Vincenzo, Wilson, Alan A, Houle, Sylvain
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Rapid Communication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367231/
https://ncbi.nlm.nih.gov/pubmed/22472607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.46
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