Translocator protein (18 kDa) polymorphism (rs6971) explains in-vivo brain binding affinity of the PET radioligand [(18)F]-FEPPA

[(18)F]-FEPPA binds to the 18-kDa translocator protein (TSPO) and is used in positron emission tomography (PET) to detect microglial activation. However, quantitative interpretations of the PET signal with new generation TSPO PET radioligands are confounded by large interindividual variability in bi...

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Detalhes bibliográficos
Main Authors: Mizrahi, Romina, Rusjan, Pablo M, Kennedy, James, Pollock, Bruce, Mulsant, Benoit, Suridjan, Ivonne, De Luca, Vincenzo, Wilson, Alan A, Houle, Sylvain
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367231/
https://ncbi.nlm.nih.gov/pubmed/22472607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.46
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