Crystal structures of the tRNA:m(2)G6 methyltransferase Trm14/TrmN from two domains of life

Methyltransferases (MTases) form a major class of tRNA-modifying enzymes needed for the proper functioning of tRNA. Recently, RNA MTases from the TrmN/Trm14 family that are present in Archaea, Bacteria and Eukaryota have been shown to specifically modify tRNA(Phe) at guanosine 6 in the tRNA acceptor...

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Bibliographic Details
Main Authors: Fislage, Marcus, Roovers, Martine, Tuszynska, Irina, Bujnicki, Janusz M., Droogmans, Louis, Versées, Wim
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367198/
https://ncbi.nlm.nih.gov/pubmed/22362751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks163
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