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Intron sequences and the length of the downstream second exon affect the binding of hnRNP C proteins in an in vitro splicing reaction.

The proteins that are in direct contact with the pre-mRNA in an in vitro splicing reaction were analyzed by UV cross-linking experiments. Six major proteins (120, 55, 44, 42, 39 and 38 KD) and three minor polypeptides (84, 72 and 63 KD) were detected. The predominant proteins 44, 42 KD belong to the...

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Autores principales: Goswami, P, Goldenberg, C J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1988
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC336712/
https://ncbi.nlm.nih.gov/pubmed/3290845
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