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Ampakines promote spine actin polymerization, long-term potentiation, and learning in a mouse model of Angelman Syndrome
Angelman syndrome (AS) is a neurodevelopmental disorder largely due to abnormal maternal expression of the UBE3A gene leading to the deletion of E6-associated protein. AS subjects have severe cognitive impairments for which there are no therapeutic interventions. Mouse models (knockouts of the mater...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367059/ https://ncbi.nlm.nih.gov/pubmed/22525571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.04.002 |
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