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Analysis and Functional Consequences of Increased Fab-Sialylation of Intravenous Immunoglobulin (IVIG) after Lectin Fractionation

It has been proposed that the anti-inflammatory effects of intravenous immunoglobulin (IVIG) might be due to the small fraction of Fc-sialylated IgG. In this study we biochemically and functionally characterized sialic acid-enriched IgG obtained by Sambucus nigra agglutinin (SNA) lectin fractionatio...

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Bibliografische gegevens
Hoofdauteurs: Käsermann, Fabian, Boerema, David J., Rüegsegger, Monika, Hofmann, Andreas, Wymann, Sandra, Zuercher, Adrian W., Miescher, Sylvia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366990/
https://ncbi.nlm.nih.gov/pubmed/22675478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037243
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