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Phosphoramidate analogues of DNA: synthesis and thermal stability of heteroduplexes.
The deoxyoligonucleotide 5' AATCGGGCATGGATT (15-mer) was synthesized containing 12 phosphoramidate linkages derived from 2 primary and 2 secondary amines. The oligonucleotides were purified by reverse phase HPLC and characterized by PAGE. The thermal stability of the duplexes derived from these...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
1988
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| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC336699/ https://ncbi.nlm.nih.gov/pubmed/3387210 |
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