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Functional Characterization of a First Avian Cytochrome P450 of the CYP2D Subfamily (CYP2D49)

The CYP2D family members are instrumental in the metabolism of 20–25% of commonly prescribed drugs. Although many CYP2D isoforms have been well characterized in other animal models, research concerning the chicken CYP2Ds is limited. In this study, a cDNA encoding a novel CYP2D enzyme (CYP2D49) was c...

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Detalhes bibliográficos
Main Authors: Cai, Hua, Jiang, Jun, Yang, Qi, Chen, Qingmei, Deng, Yiqun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366968/
https://ncbi.nlm.nih.gov/pubmed/22675558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038395
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