CXCR3 Antagonism of SDF-1(5-67) Restores Trabecular Function and Prevents Retinal Neurodegeneration in a Rat Model of Ocular Hypertension

Glaucoma, the most common cause of irreversible blindness, is a neuropathy commonly initiated by pathological ocular hypertension due to unknown mechanisms of trabecular meshwork degeneration. Current antiglaucoma therapy does not target the causal trabecular pathology, which may explain why treatme...

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Detalhes bibliográficos
Main Authors: Denoyer, Alexandre, Godefroy, David, Célérier, Isabelle, Frugier, Julie, Degardin, Julie, Harrison, Jeffrey K., Brignole-Baudouin, Francoise, Picaud, Serge, Baleux, Francoise, Sahel, José A., Rostène, William, Baudouin, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366966/
https://ncbi.nlm.nih.gov/pubmed/22675496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037873
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