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Phenotypic and Transcriptomic Response of Auxotrophic Mycobacterium avium Subsp. paratuberculosis leuD Mutant under Environmental Stress

Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of severe gastroenteritis in cattle. To gain a better understanding of MAP virulence, we investigated the role of leuD gene in MAP metabolism and stress response. For this, we have constructed an auxotrophic strain of MAP by de...

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Autori principali: Chen, Jenn-Wei, Scaria, Joy, Chang, Yung-Fu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366959/
https://ncbi.nlm.nih.gov/pubmed/22675497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037884
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