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LSK Derived LSK(–) Cells Have a High Apoptotic Rate Related to Survival Regulation of Hematopoietic and Leukemic Stem Cells
A balanced pool of hematopoietic stem cells (HSCs) in bone marrow is tightly regulated, and this regulation is disturbed in hematopoietic malignancies such as chronic myeloid leukemia (CML). The underlying mechanisms are largely unknown. Here we show that the Lin(−)Sca-1(+)c-Kit(-) (LSK(−)) cell pop...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3366951/ https://ncbi.nlm.nih.gov/pubmed/22675576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038614 |
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