Nkx3.1 Functions as Para-transcription Factor to Regulate Gene Expression and Cell Proliferation in Non-cell Autonomous Manner

Nkx3.1 is a homeoprotein transcription factor (TF) that inhibits proliferation of prostate epithelial cells (PECs) and acts as a tumor suppressor for prostate cancer (PCa). Because TFs classically function within the cells that produce them, Nkx3.1-induced growth inhibition was considered to occur i...

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Detalhes bibliográficos
Main Authors: Zhou, Jian, Qin, Li, Tien, Jean Ching-Yi, Gao, Li, Chen, Xian, Wang, Fen, Hsieh, Jer-Tsong, Xu, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366845/
https://ncbi.nlm.nih.gov/pubmed/22465996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.336909
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