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Targeted Deletion of LPA(5) Identifies Novel Roles for Lysophosphatidic Acid Signaling in Development of Neuropathic Pain

Lysophosphatidic acid (LPA) is a bioactive lipid that serves as an extracellular signaling molecule acting through cognate G protein-coupled receptors designated LPA(1–6) that mediate a wide range of both normal and pathological effects. Previously, LPA(1), a G(αi)-coupled receptor (which also coupl...

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Библиографические подробности
Главные авторы: Lin, Mu-En, Rivera, Richard R., Chun, Jerold
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366844/
https://ncbi.nlm.nih.gov/pubmed/22461625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.330183
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