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3′-Phosphoadenosine 5′-Phosphosulfate (PAPS) Synthases, Naturally Fragile Enzymes Specifically Stabilized by Nucleotide Binding

Activated sulfate in the form of 3′-phosphoadenosine 5′-phosphosulfate (PAPS) is needed for all sulfation reactions in eukaryotes with implications for the build-up of extracellular matrices, retroviral infection, protein modification, and steroid metabolism. In metazoans, PAPS is produced by bifunc...

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Detalhes bibliográficos
Main Authors: van den Boom, Johannes, Heider, Dominik, Martin, Stephen R., Pastore, Annalisa, Mueller, Jonathan W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366831/
https://ncbi.nlm.nih.gov/pubmed/22451673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.325498
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