Selective inhibition of Biotin Protein Ligase from Staphylococcus aureus

There is a well documented need to replenish the antibiotic pipeline with new agents to combat the rise of drug resistant bacteria. One strategy to combat resistance is to discover new chemical classes immune to current resistance mechanisms that inhibit essential metabolic enzymes. Many of the obvi...

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Autori principali: Soares da Costa, Tatiana P., Tieu, William, Yap, Min Y., Pendini, Nicole R., Polyak, Steven W., Sejer Pedersen, Daniel, Morona, Renato, Turnidge, John D., Wallace, John C., Wilce, Matthew C. J., Booker, Grant W., Abell, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Enzymology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366794/
https://ncbi.nlm.nih.gov/pubmed/22437830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356576
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