The thermal stability of oligonucleotide duplexes is sequence independent in tetraalkylammonium salt solutions: application to identifying recombinant DNA clones.

In solutions of tetraalkylammonium salts the melting temperature of oligonucleotide duplexes is independent of nucleotide sequence and thus GC content. Data quantitating the destabilizing effects of various mismatches in these solvents are also presented. The results are in accord with theories on D...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jacobs, K A, Rudersdorf, R, Neill, S D, Dougherty, J P, Brown, E L, Fritsch, E F
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC336654/
https://ncbi.nlm.nih.gov/pubmed/3380691
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados