Use of a Rhesus Plasmodium cynomolgi Model to Screen for Anti-Hypnozoite Activity of Pharmaceutical Substances

There remains a need for new drugs to prevent relapse of Plasmodium vivax or P. ovale infection. The relapsing primate malaria P. cynomolgi has been used for decades to assess drugs for anti-hypnozoite activity. After sporozoite inoculation and blood-stage cure of initial parasitemia with chloroquin...

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Hlavní autoři: Deye, Gregory A., Gettayacamin, Montip, Hansukjariya, Pranee, Im-erbsin, Rawiwan, Sattabongkot, Jetsumon, Rothstein, Yarrow, Macareo, Louis, Fracisco, Susan, Bennett, Kent, Magill, Alan J., Ohrt, Colin
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Tropical Medicine and Hygiene 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366535/
https://ncbi.nlm.nih.gov/pubmed/22665596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2012.11-0552
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