Phosphatase PTEN is Critically Involved in Post-Myocardial Infarction Remodeling through the Akt/Interleukin-10 Signaling Pathway

The inflammatory cytokines interleukin (IL)-10 and tumor necrosis factor (TNF)-α play an important role in left ventricular (LV) remodeling after myocardial infarction (MI). Phosphatase and tensin homologue deleted on chromosome ten (PTEN) inactivates protein kinase Akt and promotes cell death in th...

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Bibliografiske detaljer
Main Authors: Parajuli, Nirmal, Yuan, Yuan, Zheng, Xiaoxu, Bedja, Djahida, Cai, Zheqing P.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366430/
https://ncbi.nlm.nih.gov/pubmed/22298084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-012-0248-6
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