טוען...
Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis
Telomere shortening limits the proliferative capacity of a cell, but perhaps surprisingly, shortening is also known to be associated with increased rates of tumor initiation. A current hypothesis suggests that telomere dysfunction increases tumor initiation by induction of chromosomal instability, b...
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| Main Authors: | , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3366409/ https://ncbi.nlm.nih.gov/pubmed/22622037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61745 |
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