Modulation of Mouse Coagulation Gene Transcription following Acute In Vivo Delivery of Synthetic Small Interfering RNAs Targeting HNF4α and C/EBPα

Hepatocyte nuclear factor 4α (HNF4α) and CCAAT/enhancer-binding protein α (C/EBPα) are important for the transcriptional control of coagulation factors. To determine in vivo the direct role of HNF4α and C/EBPα in control of genes encoding coagulation factors, a synthetic small interfering (si)RNA ap...

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Autores principales: Safdar, Huma, Cheung, Ka Lei, Vos, Hans L., Gonzalez, Frank J., Reitsma, Pieter H., Inoue, Yusuke, van Vlijmen, Bart J. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365905/
https://ncbi.nlm.nih.gov/pubmed/22675511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038104
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