Osmotic Stress Regulates Mammalian Target of Rapamycin (mTOR) Complex 1 via c-Jun N-terminal Kinase (JNK)-mediated Raptor Protein Phosphorylation

mTOR complex 1 (mTORC1) is a multiprotein complex that integrates diverse signals including growth factors, nutrients, and stress to control cell growth. Raptor is an essential component of mTORC1 that functions to recruit specific substrates. Recently, Raptor was suggested to be a key target of reg...

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Hlavní autoři: Kwak, Dongoh, Choi, Sunkyu, Jeong, Heeyoon, Jang, Jin-Hyeok, Lee, Youngmi, Jeon, Hyeona, Lee, Mi Nam, Noh, Jungeun, Cho, Kun, Yoo, Jong Shin, Hwang, Daehee, Suh, Pann-Ghill, Ryu, Sung Ho
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365776/
https://ncbi.nlm.nih.gov/pubmed/22493283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.326538
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