Osmotic Stress Regulates Mammalian Target of Rapamycin (mTOR) Complex 1 via c-Jun N-terminal Kinase (JNK)-mediated Raptor Protein Phosphorylation

mTOR complex 1 (mTORC1) is a multiprotein complex that integrates diverse signals including growth factors, nutrients, and stress to control cell growth. Raptor is an essential component of mTORC1 that functions to recruit specific substrates. Recently, Raptor was suggested to be a key target of reg...

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Detalhes bibliográficos
Main Authors: Kwak, Dongoh, Choi, Sunkyu, Jeong, Heeyoon, Jang, Jin-Hyeok, Lee, Youngmi, Jeon, Hyeona, Lee, Mi Nam, Noh, Jungeun, Cho, Kun, Yoo, Jong Shin, Hwang, Daehee, Suh, Pann-Ghill, Ryu, Sung Ho
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365776/
https://ncbi.nlm.nih.gov/pubmed/22493283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.326538
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