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Nrf1 CNC-bZIP Protein Promotes Cell Survival and Nucleotide Excision Repair through Maintaining Glutathione Homeostasis

Skin cancer is the most common cancer in the United States. Its major environmental risk factor is UVB radiation in sunlight. In response to UVB damage, epidermal keratinocytes activate a specific repair pathway, i.e. nucleotide excision repair, to remove UVB-induced DNA lesions. However, the regula...

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Detalhes bibliográficos
Main Authors: Han, Weinong, Ming, Mei, Zhao, Rui, Pi, Jingbo, Wu, Chunli, He, Yu-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365774/
https://ncbi.nlm.nih.gov/pubmed/22500024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363614
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