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The Nrf1 CNC-bZIP Protein Is Regulated by the Proteasome and Activated by Hypoxia

BACKGROUND: Nrf1 (nuclear factor-erythroid 2 p45 subunit-related factor 1) is a transcription factor mediating cellular responses to xenobiotic and pro-oxidant stress. Nrf1 regulates the transcription of many stress-related genes through the electrophile response elements (EpREs) located in their pr...

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Detalhes bibliográficos
Main Authors: Chepelev, Nikolai L., Bennitz, Joshua D., Huang, Ting, McBride, Skye, Willmore, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244438/
https://ncbi.nlm.nih.gov/pubmed/22216197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029167
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