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Metabolic Flux of Extracellular Heme Uptake in Pseudomonas aeruginosa Is Driven by the Iron-regulated Heme Oxygenase (HemO)

Heme utilization by Pseudomonas aeruginosa involves several proteins required for internalization and degradation of heme. In the following report we provide the first direct in vivo evidence for the specific degradation of extracellular heme to biliverdin (BV) by the iron-regulated HemO. Moreover,...

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Autors principals: Barker, Kylie D., Barkovits, Katalin, Wilks, Angela
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365768/
https://ncbi.nlm.nih.gov/pubmed/22493498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359265
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