Stabilization of p53 in Influenza A Virus-infected Cells Is Associated with Compromised MDM2-mediated Ubiquitination of p53

Influenza A virus (IAV) induces apoptosis of infected cells. In response to IAV infection, p53, a tumor suppressor involved in regulating apoptosis and host antiviral defense, accumulates and becomes activated. This study was undertaken to examine the mechanism of p53 accumulation in IAV-infected ce...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wang, Xiaodu, Deng, Xufang, Yan, Wenjun, Zhu, Zixiang, Shen, Yang, Qiu, Yafeng, Shi, Zixue, Shao, Donghua, Wei, Jianchao, Xia, Xianzhu, Ma, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365762/
https://ncbi.nlm.nih.gov/pubmed/22474335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.335422
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados