Functional Interaction of CD154 Protein with α5β1 Integrin Is Totally Independent from Its Binding to αIIbβ3 Integrin and CD40 Molecules

In addition to its classical CD40 receptor, CD154 also binds to αIIbβ3, α5β1, and αMβ2 integrins. Binding of CD154 to these receptors seems to play a key role in the pathogenic processes of chronic inflammation. This investigation was aimed at analyzing the functional interaction of CD154 with CD40,...

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Bibliographische Detailangaben
Hauptverfasser: El Fakhry, Youssef, Alturaihi, Haydar, Yacoub, Daniel, Liu, Lihui, Guo, Wenyan, Leveillé, Claire, Jung, Daniel, Khzam, Lara Bou, Merhi, Yahye, Wilkins, John A., Li, Hongmin, Mourad, Walid
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365732/
https://ncbi.nlm.nih.gov/pubmed/22461623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.333989
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