Replication of Hepatitis C Virus RNA on Autophagosomal Membranes

Previous studies indicated that hepatitis C virus (HCV) perturbs the autophagic pathway to induce the accumulation of autophagosomes in cells. To understand the role of autophagosomes in the HCV life cycle, we established a stable Huh7 hepatoma cell line that contained an HCV subgenomic RNA replicon...

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Autors principals: Sir, Donna, Kuo, Cheng-fu, Tian, Yongjun, Liu, Helene Minyi, Huang, Eric J., Jung, Jae U., Machida, Keigo, Ou, Jing-hsiung James
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365724/
https://ncbi.nlm.nih.gov/pubmed/22496373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.320085
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