Autophagy Required for Hepatitis B Virus Replication in Transgenic Mice

Recent studies indicate that hepatitis B virus (HBV) may induce autophagy to enhance its replication in cell cultures. To understand whether autophagy can indeed enhance HBV replication in vivo, we generated HBV transgenic mice with liver-specific knockout of the Atg5 gene, a gene critical for the i...

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Bibliografiske detaljer
Main Authors: Tian, Yongjun, Sir, Donna, Kuo, Cheng-fu, Ann, David K., Ou, Jing-hsiung James
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233133/
https://ncbi.nlm.nih.gov/pubmed/21957292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06064-11
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